Level Select
At the Cheats screen, press Circle, X, Square, Square, X, Square, Circle.
Invincibility
At the Cheats screen, press L1, Square, Circle, Circle, Square, L1, L2.
All Weapons
At the Cheats screen, press R2, X, L1, Square, R1, Circle, L2.
Infinite Ammo
At the Cheats screen, press L2, Circle, R2, Square, Circle, L2, R1.
Double Damage
At the Cheats screen, press Square, Square, Square, Circle, Circle, Circle, X.
Temporary Invincibility
At the Cheats screen, press L1, L1, L1, L1, L1, L1, R2.
Invisibility
At the Cheats screen, press Square, X, Circle, Square, X, Circle, Square.
Full Ego
At the Cheats screen, press R1, R1, Circle, Circle, L1, L1, R2.
Full Armor
At the Cheats screen, press L1, L1, R1, R1, X, X, Circle, Circle.
First Person View
At the Cheats screen, press L2, R1, L1, R2, Circle, X, Square.
Big Head Duke
At the Cheats screen, press Square, Square, X, Circle, Circle, X, Square.
Small Head Duke
At the Cheats screen, press Square, X, Circle, Circle, X, Square, Square.
Big Head Enemies
At the Cheats screen, press X, X, R1, X, L1, X.
Small Head Enemies
At the Cheats screen, press X, L1, X, R1, X, X.
Wacky FMV Sequences
At the Cheats screen, press L1, L2, R1, R2, Circle, Circle, Square, Square.
Outtake FMV Sequences
At the Cheats screen, press L1, L2, R1, R2, Square, Square, Circle, Circle.
Ending FMV Sequence
At the Cheats screen, press Circle, R2, L1, Square, L2, X, R2.
Unlock All Cheats
At the Cheats screen, press L1, L2, R2, R1, L1, L2, R2, R1, L1, L2, R2, R1, L1, L2, R2, R1, Circle, Circle, Circle, Circle, X, X, X, X, Square, Square, Square, Square, Select, Select, Select, Select.